SuperDuper!


(from the site)


Carbon copies. And a whole lot more.

SuperDuper is the most advanced, yet easy to use disk copying program available for OS X. It can, of course, make a full backup, or "clone" in moments, you can completely duplicate your boot drive to another drive, partition, or image file. In even less time, you can update an existing clone with the latest data: use Smart Update and, minutes later, your backup is completely up to date!