SuperDuper!


(from the site)


Carbon copies. And a whole lot more.

SuperDuper is the most advanced, yet easy to use disk copying program available for OS X. It can, of course, make a full backup, or "clone" — in moments, you can completely duplicate your boot drive to another drive, partition, or image file. In even less time, you can update an existing clone with the latest data: use Smart Update and, minutes later, your backup is completely up to date!